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Translational Medicine / 转化医学CLL BTK Resistance Research

Jennifer Brown

MD, PhD

🏢Dana-Farber Cancer Institute🌐USA

Director, CLL Center

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Key Contributions

👥Biography 个人简介

Jennifer Brown is a leading CLL researcher who directs one of the largest CLL programs globally. Her work on BTK inhibitor resistance mechanisms and the development of non-covalent BTK inhibitors has been transformative. She has led pivotal clinical trials of pirtobrutinib demonstrating activity in covalent BTK inhibitor-resistant CLL.

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🧪Research Fields 研究领域

CLL targeted therapy
BTK inhibitor resistance
Pirtobrutinib
Venetoclax combinations
CLL biology

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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