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Translational Medicine / 转化医学Genitourinary Oncology, RCC Systemic Therapy

Brian Rini

MD

🏢Vanderbilt University Medical Center🌐USA

Professor of Medicine, Chief of Genitourinary Oncology

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Key Contributions

👥Biography 个人简介

Brian Rini has made defining contributions to systemic therapy for advanced renal cell carcinoma, from establishing sunitinib as a benchmark to leading KEYNOTE-426 that changed the frontline standard of care with pembrolizumab plus axitinib. His research has explored biomarkers of IO response in RCC and combination TKI/IO strategies. He has been a principal investigator on more RCC registration trials than virtually any other investigator in the field.

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🧪Research Fields 研究领域

RCC systemic therapy
sunitinib RCC
pembrolizumab axitinib KEYNOTE-426
RCC IO combination frontline
VEGFR TKI RCC

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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