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Translational Medicine / 转化医学B Cell Biology, CLL

Brian Bhatt

MD

🏢Ohio State University Comprehensive Cancer Center🌐USA

Professor of Hematology

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Key Contributions

👥Biography 个人简介

Brian Bhatt specializes in the biology and treatment of chronic lymphocytic leukemia, with emphasis on BCR signaling and therapeutic targeting. His research has characterized CLL cell dependence on microenvironmental BCR signals and developed strategies to disrupt these interactions. He has investigated mechanisms of Richter transformation from CLL to aggressive lymphoma. His clinical research has advanced BTK inhibitor therapy combinations and identified biomarkers of resistance and transformation.

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🧪Research Fields 研究领域

chronic lymphocytic leukemia
BCR signaling in CLL
BTK inhibition
Richter transformation
minimal residual disease

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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