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Translational Medicine / 转化医学T-Cell Engager, Toxicity Management

Brendan Roddy

MD

🏢Stanford Cancer Institute🌐USA

Medical Oncologist and Immunotherapy Safety Specialist

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Key Contributions

👥Biography 个人简介

Dr. Brendan Roddy specializes in the safety and toxicity management of T-cell engaging bispecific antibodies. He has contributed to defining grading and management protocols for cytokine release syndrome and immune effector cell-associated neurotoxicity syndrome (ICANS) arising from bispecific antibody therapies. His work on step-up dosing strategies has enabled safer outpatient administration of bispecific antibodies in both hematologic and solid tumor settings.

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🧪Research Fields 研究领域

cytokine release syndrome BiTE management
immune effector cell toxicity bispecific
ICANS bispecific antibody
toxicity mitigation step-up dosing
bispecific antibody safety solid tumors

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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