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Translational Medicine / 转化医学Oncolytic Virus, RP2 RP3 Armed Oncolytic

Brendan Curti

MD

🏢Providence Cancer Institute🌐USA

Director, Cancer Immunotherapy Program

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Key Contributions

👥Biography 个人简介

Brendan Curti has led early-phase clinical evaluation of next-generation armed oncolytic herpes viruses including RP2 and RP3 in solid tumors. His work has characterized the immune-activating consequences of intratumoral oncolytic virus delivery and the potential for systemic abscopal responses. He has contributed to defining safety profiles and preliminary efficacy signals for engineered oncolytic virus platforms.

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🧪Research Fields 研究领域

RP2 RP3 armed oncolytic herpesvirus
intratumoral oncolytic virus solid tumor
anti-CTLA4 encoding oncolytic virus
oncolytic immunooncology combinations
phase I oncolytic virus melanoma

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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