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Translational Medicine / 转化医学MMR Biochemical Mechanisms

Bogdan Fedeles

PhD

🏢MIT🌐USA

Research Scientist

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Key Contributions

👥Biography 个人简介

Bogdan Fedeles investigates the biochemical mechanisms by which MMR deficiency drives mutagenesis and the generation of neoantigen-rich MSI-H tumors. His work bridges MMR enzymology and the clinical immunotherapy responses seen in dMMR cancers.

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🧪Research Fields 研究领域

MMR biochemistry
DNA damage
mutagenesis
dMMR tumors
DNA repair mechanism

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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