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Translational Medicine / 转化医学Spatial Proteomics

Bernd Bodenmiller

PhD

🏢University of Zurich🌐Switzerland

Professor of Quantitative Biomedicine

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Key Contributions

👥Biography 个人简介

Bernd Bodenmiller pioneered imaging mass cytometry (IMC) for spatial proteomics, enabling simultaneous detection of over 40 protein markers in tissue sections at subcellular resolution. His application of IMC to breast cancer revealed that the spatial organization of immune and stromal cells, rather than their mere abundance, determines clinical outcome. His systematic mapping of tumor microenvironment architecture has identified spatial biomarkers predictive of treatment response that are invisible to bulk tissue analysis.

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🧪Research Fields 研究领域

Imaging mass cytometry
Tumor microenvironment spatial analysis
Breast cancer tissue mapping
Metal-tagged antibody imaging
Single-cell spatial proteomics

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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