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Translational Medicine / 转化医学Repotrectinib, ROS1/NTRK Resistance

Bob Li

MD, PhD, MPH

🏢Memorial Sloan Kettering Cancer Center🌐USA

Thoracic Oncologist

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Key Papers
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Key Contributions

👥Biography 个人简介

Bob Li at Memorial Sloan Kettering focuses on targeted therapy for lung cancer, particularly overcoming resistance to first-generation ROS1 and NTRK inhibitors. He was a key investigator on the TRIDENT-1 trial of repotrectinib for ROS1 and NTRK fusion-positive NSCLC. His research defines mechanisms of acquired resistance and next-generation inhibitor strategies.

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🧪Research Fields 研究领域

repotrectinib TPX-0005
ROS1 inhibitors
NTRK resistance
next-generation TKI
lung cancer molecular

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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