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Translational Medicine / 转化医学HER2-Mutant NSCLC

Bob Li

MD, PhD, MPH

🏢Memorial Sloan Kettering Cancer Center🌐USA

Attending Physician and Associate Professor

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Key Contributions

👥Biography 个人简介

Bob Li led DESTINY-Lung01 and DESTINY-Lung02 establishing trastuzumab deruxtecan (T-DXd) as the first approved targeted therapy for HER2-mutant NSCLC. His work defined HER2 exon 20 insertions as actionable alterations and transformed outcomes for this patient population. He continues to study HER2 ctDNA monitoring and resistance mechanisms.

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🧪Research Fields 研究领域

HER2 exon 20 NSCLC
trastuzumab deruxtecan lung
DESTINY-Lung01/02
HER2 ctDNA NSCLC
HER2 mutation biology

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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