Bert Vogelstein
MD
Clayton Professor
👥Biography 个人简介
Bert Vogelstein at Johns Hopkins established the genetic model of colorectal cancer through sequential accumulation of mutations in driver genes (APC, KRAS, SMAD4, TP53), creating the paradigm for multi-step carcinogenesis. His decades of landmark contributions — including TP53 characterization, cancer driver gene discovery, and CancerSEEK multi-cancer early detection — have been among the most foundational in cancer biology.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-03-01 | All information from publicly available academic sources
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