Bert Vogelstein
MD
Clayton Professor of Oncology and Pathology
👥Biography 个人简介
Bert Vogelstein defined the multi-step model of colorectal carcinogenesis and identified p53 as the most commonly mutated gene in human cancer. His work established the genetic basis of cancer progression through sequential accumulation of oncogene activations and tumor suppressor losses. He pioneered liquid biopsy approaches using circulating tumor DNA for early cancer detection, transforming cancer diagnostics.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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