Bert Vogelstein
MD
Professor of Oncology and Pathology
👥Biography 个人简介
Bert Vogelstein characterized the multi-step genetic model of colorectal cancer, establishing APC mutations as the initiating event that activates WNT/beta-catenin signaling. His work defined the adenoma-carcinoma sequence and identified key driver mutations. He pioneered liquid biopsy approaches for early cancer detection and continues to advance precision oncology. His cancer genomics work has fundamentally shaped understanding of WNT-driven colorectal tumorigenesis.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-03-01 | All information from publicly available academic sources
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