Benjamin Besse
本雅明·贝塞
MD, PhD
Head of Thoracic Oncology Department胸部肿瘤科主任
👥Biography 个人简介
Leading European thoracic oncologist bridging pathology biomarkers and clinical trial design. Director of landmark studies incorporating tumor tissue and liquid biopsy biomarkers into lung cancer clinical decision-making, advancing predictive marker-driven trial stratification globally.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Biomarker-Driven Lung Cancer Trials
Designed and led European biomarker-stratified lung cancer trials integrating tissue NGS and liquid biopsy endpoints, establishing paradigms for adaptive biomarker-selected trial design in thoracic oncology.
Circulating Tumor DNA Clinical Utility
Demonstrated clinical utility of ctDNA for monitoring treatment response and early relapse detection in NSCLC, supporting integration of liquid biopsy into routine oncology practice across Europe.
Representative Works 代表性著作
ctDNA as an Early Efficacy Biomarker in Advanced NSCLC Treated with Immune Checkpoint Inhibitors
Annals of Oncology (2024)
Prospective validation of early ctDNA clearance as a surrogate biomarker for durable benefit from pembrolizumab in advanced NSCLC.
Comprehensive Tumor Molecular Profiling and Clinical Outcomes in the MOSCATO-01 Trial
Journal of Clinical Oncology (2023)
Demonstrated feasibility and clinical benefit of molecularly matched therapy guided by comprehensive genomic profiling in refractory lung cancer patients.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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