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Translational Medicine / 转化医学Neoantigen-DC Vaccine, Personalized Immunotherapy

Beatriz Carreno

PhD

🏢University of Pennsylvania🌐USA

Associate Professor of Medicine

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Key Contributions

👥Biography 个人简介

Beatriz Carreno pioneered neoantigen-loaded dendritic cell vaccines for personalized cancer immunotherapy, demonstrating in a landmark study that DCs pulsed with patient-specific neoantigens can expand neoantigen-reactive T cells in melanoma patients. Her approach of computationally predicting neoantigens and loading them onto autologous DCs established a template for personalized DC vaccine therapy. She has contributed to optimizing neoantigen selection algorithms for DC vaccine applications. Her translational research bridges computational neoantigen prediction with cellular immunotherapy.

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🧪Research Fields 研究领域

neoantigen DC vaccine cancer
personalized dendritic cell vaccine
tumor neoantigen loading DC
DC vaccine melanoma neoantigen
MHC peptide DC therapy

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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