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Translational Medicine / 转化医学Melanoma Immunotherapy 2026

Bart Neyns

巴特·内恩斯

MD, PhD

🏢UZ Brussel (Universitair Ziekenhuis Brussel), Vrije Universiteit Brussel(布鲁塞尔大学医院/布鲁塞尔自由大学)🌐Belgium

Head, Department of Medical Oncology; Professor of Medical Oncology肿瘤内科系主任;肿瘤内科学教授

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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Bart Neyns at UZ Brussel is Belgium's leading melanoma oncologist and a key European contributor to ipilimumab and nivolumab pivotal trials. He has championed access to immunotherapy for Belgian patients and led studies on melanoma brain metastases, establishing immunotherapy as effective in this historically poor-prognosis setting.

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🧪Research Fields 研究领域

Ipilimumab Nivolumab Melanoma Belgium比利时黑色素瘤伊匹单抗与纳武利尤单抗治疗
European Melanoma Immunotherapy Trials欧洲黑色素瘤免疫治疗临床试验
Melanoma Brain Metastases Immunotherapy黑色素瘤脑转移免疫治疗

🎓Key Contributions 主要贡献

European Melanoma Immunotherapy Trials

Principal investigator for ipilimumab and nivolumab pivotal trials at UZ Brussel, contributing to European regulatory approvals and establishing local immunotherapy infrastructure for advanced melanoma.

Melanoma Brain Metastases

Led and contributed to CheckMate 204 and ABC trials demonstrating clinically meaningful intracranial responses with nivolumab+ipilimumab in melanoma patients with brain metastases.

Representative Works 代表性著作

[1]

Ipilimumab in Patients with Melanoma and Brain Metastases: An Open-Label, Phase 2 Trial

The Lancet Oncology (2012)

Demonstrated activity of ipilimumab in melanoma brain metastases, opening checkpoint blockade for a population with extremely poor prognosis.

[2]

Nivolumab plus Ipilimumab in Melanoma Metastatic to the Brain (CheckMate 204)

New England Journal of Medicine (2019)

Established dual checkpoint blockade as effective and durable in active brain metastases, redefining treatment options for this high-risk subgroup.

🏆Awards & Recognition 奖项与荣誉

🏆Belgian Society of Medical Oncology (BSMO) Award for Excellence
🏆Melanoma World Society Recognition Award
🏆Kom op tegen Kanker Research Grant

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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