Barbara Eichhorst
芭芭拉·艾希霍斯特
MD
Professor of Internal Medicine; Deputy Director, Department I of Internal Medicine (Hematology/Oncology)内科学教授兼内科一部（血液/肿瘤）副主任
👥Biography 个人简介
Prof. Barbara Eichhorst is Germany's pre-eminent CLL clinician-scientist and a key investigator of the German CLL Study Group (GCLLSG). She led the CLL10 trial establishing obinutuzumab-chlorambucil as a superior frontline CLL regimen and has driven multiple practice-changing European CLL trials.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
CLL10 Trial and Obinutuzumab
Led the GCLLSG CLL10 trial demonstrating obinutuzumab-chlorambucil superiority over rituximab-chlorambucil in frontline CLL, establishing obinutuzumab as the preferred CD20 antibody for elderly/unfit patients.
GCLLSG Trial Leadership
Has led or co-led multiple GCLLSG phase 3 trials including CLL8, CLL10, and CLL13, collectively establishing FCR, then obinutuzumab-based, then venetoclax-based regimens as successive standards of CLL care.
Representative Works 代表性著作
Obinutuzumab plus Chlorambucil in Patients with CLL and Coexisting Conditions (CLL10 and CLL11)
New England Journal of Medicine (2014)
Phase 3 trial demonstrating obinutuzumab-chlorambucil improves PFS versus rituximab-chlorambucil in elderly CLL patients.
First-Line Chemoimmunotherapy with Bendamustine and Rituximab versus Fludarabine, Cyclophosphamide, and Rituximab in Patients with Advanced CLL (CLL10)
Lancet Oncology (2016)
CLL10 trial showing comparable efficacy but improved tolerability of BR versus FCR in physically fit frontline CLL patients.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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