Aziz Sancar
MD PhD
Sarah Graham Kenan Professor
👥Biography 个人简介
Aziz Sancar shared the 2015 Nobel Prize for mechanistically elucidating nucleotide excision repair (NER) — the cellular pathway that removes bulky DNA lesions including UV-induced pyrimidine dimers and platinum-DNA adducts (from cisplatin). His discovery of the prokaryotic and eukaryotic NER machinery has been essential for understanding why NER deficiency causes xeroderma pigmentosum and why cisplatin remains active or resistant in different cancer contexts.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-03-01 | All information from publicly available academic sources
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