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Translational Medicine / 转化医学Colorectal Cancer, Refractory Treatment

Axel Grothey

MD

🏢West Cancer Center and Research Institute🌐USA

Director of GI Cancer Research

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Key Contributions

👥Biography 个人简介

Axel Grothey is a pioneer in the treatment of refractory colorectal cancer, having led the CORRECT trial that established regorafenib and the RECOURSE trial that established TAS-102/trifluridine-tipiracil as approved salvage therapies. His clinical trial leadership has significantly expanded the therapeutic landscape for patients who progress on standard regimens. He has been instrumental in developing treatment algorithms and sequencing strategies for advanced CRC. His work on maintenance therapy and chemotherapy holidays has also shaped CRC management.

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🧪Research Fields 研究领域

regorafenib colorectal cancer
TAS-102 trifluridine CRC
CORRECT trial regorafenib
RECOURSE trial TAS-102
refractory CRC management

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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