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Translational Medicine / 转化医学Colorectal Cancer, Adjuvant ctDNA Guidance

Axel Grothey

MD

🏢West Cancer Center🌐USA

Director, GI Oncology Program

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Key Contributions

👥Biography 个人简介

Dr. Axel Grothey is a GI oncologist with extensive expertise in colorectal cancer treatment and a leader in ctDNA-guided adjuvant therapy approaches. He has contributed to analyses of circulating tumor DNA as a minimal residual disease biomarker to personalize adjuvant chemotherapy decisions in stage II-III colon cancer. His work on the CIRCULATE and DYNAMIC trial concepts has shaped the emerging paradigm of ctDNA-adaptive colon cancer management.

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🧪Research Fields 研究领域

colon cancer adjuvant therapy
ctDNA-guided adjuvant colorectal
minimal residual disease colon
CIRCULATE trial ctDNA
stage II-III colon surveillance ctDNA

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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