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Translational Medicine / 转化医学Colorectal Cancer, Adjuvant

Axel Grothey

MD

🏢West Cancer Center and Research Institute🌐USA

Medical Director, West Cancer Center

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Key Contributions

👥Biography 个人简介

Axel Grothey contributed to the IDEA North American consortium and has been a leading advocate for risk-stratified adjuvant duration in stage III colon cancer based on IDEA trial results. His research on minimizing cumulative neuropathy while maintaining oncological outcomes has influenced widespread adoption of 3-month CAPOX in low-risk stage III colon cancer. He has contributed to multiple practice-changing publications on adjuvant and metastatic CRC therapy. Grothey is widely recognized for translating complex clinical trial data into practical treatment algorithms for colorectal oncology.

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🧪Research Fields 研究领域

IDEA collaboration adjuvant CRC
6 months FOLFOX toxicity adjuvant
adjuvant oxaliplatin neuropathy
stage III high-risk versus low-risk adjuvant
capecitabine oxaliplatin adjuvant CRC

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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