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Translational Medicine / 转化医学Anti-Angiogenic Therapy, VEGF Pathway Biology

Axel Bhatt

PhD

🏢Genentech / Roche🌐USA

Research Scientist

21
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Key Contributions

👥Biography 个人简介

Dr. Axel Bhatt is a molecular biologist at Genentech who studies VEGF family member biology beyond VEGF-A, including VEGF-C, VEGF-D, and PlGF in cancer angiogenesis and lymphangiogenesis. He has investigated how VEGFR1 acts as a decoy receptor modulating VEGF bioavailability and examined alternative angiogenic compensatory pathways that emerge following anti-VEGF treatment. His work on VEGF biology informs combination anti-angiogenic strategies.

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🧪Research Fields 研究领域

VEGF alternative isoforms cancer
placental growth factor PLGF
VEGF-C VEGF-D lymphangiogenesis
VEGFR1 decoy receptor tumor
anti-angiogenic drug resistance biology

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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