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Cell Therapy / 细胞治疗Next-Generation Cell Therapy

Aude Chapuis

奥德·沙普伊

MD

🏢Fred Hutchinson Cancer Center(弗雷德·哈钦森癌症研究中心)🌐USA

Associate Professor, Translational Science and Therapeutics转化科学与治疗学副教授

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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Leader in antigen-specific T-cell receptor (TCR) therapies targeting viral and tumor antigens. Pioneered clinical use of CMV-specific TCR-redirected T cells and developed adoptive T-cell platforms for hematologic malignancies and solid tumors.

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🧪Research Fields 研究领域

TCR-Engineered T-Cell TherapyTCR工程T细胞治疗
Antigen-Specific T-Cell Therapy抗原特异性T细胞治疗
CMV-Specific ImmunotherapyCMV特异性免疫治疗

🎓Key Contributions 主要贡献

CMV-Specific TCR-T Therapy

Developed and clinically validated TCR-redirected T-cell strategies using CMV antigens as surrogate tumor targets, demonstrating potent anti-tumor efficacy in myeloid malignancies.

Representative Works 代表性著作

[1]

Tracking the Fate and Origin of Clinically Relevant Adoptively Transferred CD8+ T Cells In Vivo

Science Immunology (2017)

Provided key insights into in vivo persistence and trafficking of adoptively transferred antigen-specific T cells.

🏆Awards & Recognition 奖项与荣誉

🏆NIH Pathway to Independence Award
🏆Fred Hutch Translational Research Award

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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