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Translational Medicine / 转化医学CROSS Protocol, Trimodality Esophageal

Ate van der Gaast

MD, PhD

🏢Erasmus MC Cancer Institute🌐Netherlands

Professor of Medical Oncology

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Key Contributions

👥Biography 个人简介

Ate van der Gaast at Erasmus MC led the CROSS trial, establishing preoperative carboplatin/paclitaxel with concurrent radiotherapy (the CROSS regimen) as the standard neoadjuvant treatment for resectable esophageal cancer. This landmark trial demonstrated significant improvements in pathologic complete response rates and overall survival. His work has been adopted globally as the primary standard of care for locally advanced resectable esophageal cancer.

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🧪Research Fields 研究领域

CROSS protocol esophageal
trimodality therapy esophageal
neoadjuvant chemoradiation esophageal
carboplatin paclitaxel esophageal
local control esophageal

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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