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Translational Medicine / 转化医学Soft Tissue Sarcoma, Epithelioid Sarcoma

Arthur Staddon

MD

🏢Abramson Cancer Center, University of Pennsylvania🌐USA

Associate Professor of Medicine

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Key Contributions

👥Biography 个人简介

Arthur Staddon has contributed to clinical evaluation of tazemetostat (an EZH2 inhibitor) in SMARCB1-deficient epithelioid sarcoma, a rare and aggressive soft tissue tumor predominantly affecting young adults. His work contributed to the FDA approval of tazemetostat for epithelioid sarcoma based on single-arm basket trial data. He participates in rare sarcoma clinical trials and multi-institutional outcome registries.

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🧪Research Fields 研究领域

epithelioid sarcoma tazemetostat
SMARCB1 loss sarcoma
EZH2 inhibitor sarcoma
epithelioid sarcoma biology
rare sarcoma targeted therapy

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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