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Translational Medicine / 转化医学TLR Agonists, Innate Immunity

Arthur Krieg

MD

🏢Checkmate Pharmaceuticals (Regeneron)🌐USA

Chief Scientific Officer

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Key Papers
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Key Contributions

👥Biography 个人简介

Arthur Krieg discovered immunostimulatory CpG DNA and pioneered TLR9 agonist development for cancer. His intratumoral TLR9 agonists are being tested to inflame cold tumors and prime checkpoint-inhibitor responses. He is recognized as a founder of oligonucleotide-based innate immune activation.

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🧪Research Fields 研究领域

TLR9 agonist
CpG oligonucleotides
innate immune activation
intratumoral immunotherapy
cold tumor inflammation

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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