Arnold Levine
PhD
Professor Emeritus
👥Biography 个人简介
Arnold Levine co-discovered p53 in 1979 — the most commonly mutated gene in human cancer, altered in over 50% of all cancers. p53's role as the 'guardian of the genome' — activating DNA damage responses, cell cycle arrest, and apoptosis — makes it central to understanding how cancer evades normal cellular safeguards. His foundational work on p53 biology and MDM2-mediated p53 regulation has been among the most impactful in all of cancer biology.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-03-01 | All information from publicly available academic sources
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