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Translational Medicine / 转化医学HNSCC Systemic Chemotherapy, Concurrent CRT

Arlene Forastiere

MD

🏢Johns Hopkins Sidney Kimmel Comprehensive Cancer Center🌐USA

Professor Emeritus of Oncology

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Key Contributions

👥Biography 个人简介

Arlene Forastiere is a pioneer in head and neck cancer systemic therapy at Johns Hopkins who led the landmark RTOG 91-11 trial establishing concurrent cisplatin chemoradiation as the larynx preservation standard of care. Her work transformed management of locally advanced laryngeal cancer and influenced treatment paradigms across all HNSCC subsites. She has contributed to defining cisplatin-based regimens and their role in organ preservation strategies for decades. Her clinical trial leadership has shaped the foundational treatment algorithms still used today.

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🧪Research Fields 研究领域

concurrent chemoradiation HNSCC
cisplatin HNSCC
larynx preservation
RTOG 91-11 trial
head and neck cancer systemic therapy

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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