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Translational Medicine / 转化医学ctDNA Lymphoma, clonoSEQ

Arash Alizadeh

MD PhD

🏢Stanford University🌐USA

Professor

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👥Biography 个人简介

Arash Alizadeh at Stanford developed CAPP-Seq alongside Maximilian Diehn and applied it extensively to lymphoma ctDNA monitoring. His research demonstrating that ctDNA kinetics during treatment predict outcomes in DLBCL and other lymphomas, and his work on ibrutinib resistance mutation detection from ctDNA in CLL, have established ctDNA as a powerful monitoring tool in hematologic malignancies. His commercialization of clonoSEQ for MRD detection in blood cancers represents a successful liquid biopsy clinical translation.

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🧪Research Fields 研究领域

ctDNA lymphoma MRD
CAPP-Seq lymphoma
MRD lymphoma liquid biopsy
diffuse large B cell lymphoma ctDNA
ibrutinib resistance ctDNA

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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