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Translational Medicine / 转化医学Oncolytic Virus, Oncolytic Adenovirus GBM

Antonio Chiocca

MD, PhD

🏢Brigham and Women's Hospital🌐USA

Neurosurgeon-in-Chief, Department of Neurosurgery

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👥Biography 个人简介

Antonio Chiocca is a neurosurgeon and virologist who has pioneered intratumoral oncolytic adenovirus delivery for GBM. His laboratory has explored engineering strategies to enhance the selectivity and potency of oncolytic adenoviruses for malignant brain tumors. He has contributed to multiple clinical trials of oncolytic viruses for GBM and led research on combining oncolytic virotherapy with radiation and checkpoint immunotherapy.

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🧪Research Fields 研究领域

oncolytic adenovirus GBM
CAN-2409 prodrug gene therapy
oncolytic virus neurosurgical delivery
GBM combination oncolytic IO
adenovirus engineering cancer

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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