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Translational Medicine / 转化医学HBV Therapy, Hepatocellular Carcinoma Prevention

Anna Lok

MD

🏢University of Michigan🌐USA

Alice Lohrman Andrews Research Professor in Hepatology

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Key Contributions

👥Biography 个人简介

Anna Lok is a world-leading authority on hepatitis B virus infection and the prevention of HBV-associated hepatocellular carcinoma. Her landmark research established that long-term nucleoside/nucleotide analog therapy suppressing HBV replication significantly reduces HCC incidence in patients with chronic hepatitis B and cirrhosis. She has contributed to the development and evaluation of tenofovir, entecavir, and other antivirals for HBV and has defined optimal treatment paradigms for different patient populations. Her extensive epidemiological and clinical studies have informed national and international HBV treatment guidelines and HCC prevention programs globally.

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🧪Research Fields 研究领域

HBV treatment
HCC prevention
nucleos(t)ide analogs
tenofovir entecavir
liver cancer screening

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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