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Translational Medicine / 转化医学NSCLC, ROS1 Next-Generation Inhibitors

Anna F. Farago

MD, PhD

🏢Massachusetts General Hospital, Harvard Medical School🌐USA

Assistant Professor of Medicine

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Key Contributions

👥Biography 个人简介

Anna Farago is a thoracic oncologist and translational researcher specializing in ROS1-rearranged NSCLC and strategies to overcome acquired resistance to first-generation ROS1 inhibitors. Her work has characterized solvent-front resistance mutations in ROS1 and evaluated next-generation inhibitors including repotrectinib. She has contributed to multi-institutional studies characterizing the natural history and molecular evolution of ROS1-positive tumors. Her research bridges laboratory mechanistic studies and early-phase clinical trial design.

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🧪Research Fields 研究领域

ROS1 rearrangements
repotrectinib
ROS1 resistance mutations
entrectinib ROS1
NTRK/ROS1 overlap

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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