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Translational Medicine / 转化医学Tissue Factor, Cancer Coagulation

Anna Falanga

MD

🏢University of Milan-Bicocca / Hospital Papa Giovanni XXIII🌐Italy

Professor of Hematology

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Key Contributions

👥Biography 个人简介

Anna Falanga has been a leader in understanding how cancer cells activate the coagulation system through tissue factor expression and release of procoagulant microparticles, establishing the mechanistic links between cancer biology and thrombosis. Her research demonstrated that tissue factor-bearing microparticles from cancer cells activate platelets and the coagulation cascade in the circulation. She has contributed to understanding how chemotherapy and targeted therapies modulate thrombotic risk. Her work provides the biological rationale for thromboprophylaxis in cancer patients.

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🧪Research Fields 研究领域

tissue factor cancer coagulation
cancer procoagulant activity
TF microparticle cancer
coagulation activation cancer biology
platelet cancer cell interaction

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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