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Translational Medicine / 转化医学HCC Regorafenib, Second-Line TKI Therapy

Ann-Lii Cheng

MD, PhD

🏢National Taiwan University Hospital🌐Taiwan

Professor; Director, National Taiwan University Cancer Center

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Key Contributions

👥Biography 个人简介

Ann-Lii Cheng is a pioneer in advanced hepatocellular carcinoma clinical trials who led the Asia/Pacific sorafenib SHARP trial and the RESORCE trial establishing regorafenib as the first second-line agent in sorafenib-progressed HCC. His work has been essential in demonstrating that findings from predominantly Western or mixed population trials are applicable to hepatitis B-related HCC prevalent in Asia. He has led or participated in most major HCC systemic therapy trials over two decades and is a central figure in Asia-Pacific oncology.

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🧪Research Fields 研究领域

regorafenib HCC RESORCE trial
sorafenib Asia HCC clinical trials
NLCN linifanib HCC
HCC second-line TKI therapy
hepatitis B-related HCC Asian epidemiology

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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