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Translational Medicine / 转化医学MDS & AML

Andrew Wei

安德鲁·韦

MBBS, PhD, FRACP, FRCPA

🏢Alfred Hospital / Monash University(阿尔弗雷德医院 / 莫纳什大学)🌐Australia

Professor and Head of Haematology血液科教授及主任

58
h-index
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Key Papers
3
Awards
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Key Contributions

👥Biography 个人简介

Andrew Wei is Australia's foremost AML researcher and a global leader in BCL-2 inhibition and venetoclax-based regimens. He co-led the pivotal VIALE-A trial and has advanced MRD-guided therapy and novel combination strategies in AML.

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🧪Research Fields 研究领域

Acute Myeloid Leukemia急性髓系白血病
Venetoclax plus Azacitidine维奈克拉联合阿扎胞苷
AML MRDAML微小残留病灶
BCL-2 InhibitorsBCL-2抑制剂
VIALE-AVIALE-A研究

🎓Key Contributions 主要贡献

VIALE-A Trial Leadership

Co-led the international VIALE-A phase III trial demonstrating venetoclax plus azacitidine nearly doubled overall survival versus azacitidine alone in treatment-naive unfit AML patients.

MRD in AML

Advanced multiparameter flow cytometry and molecular MRD assessment in AML, establishing MRD negativity as a key surrogate endpoint for durable remission in venetoclax-based trials.

Representative Works 代表性著作

[1]

Venetoclax plus Azacitidine versus Azacitidine in Untreated AML (VIALE-A)

New England Journal of Medicine (2020)

Landmark trial establishing the venetoclax–azacitidine combination as a new global standard for older or unfit AML patients, with improved OS and CR rates.

[2]

Molecular Minimal Residual Disease and the Kinetics of BCL-2 Inhibition in AML

Blood (2021)

Demonstrated the prognostic relevance of MRD clearance with venetoclax-based therapy, informing MRD-guided treatment strategies.

🏆Awards & Recognition 奖项与荣誉

🏆HSANZ Dameshek Prize
🏆NHMRC Investigator Grant (Leadership Level)
🏆Victorian Cancer Agency Translational Research Award

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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