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Translational Medicine / 转化医学Immunosuppression, FOXP3 Regulation

Andrew Bhatt

PhD

🏢Harvard Medical School🌐USA

Associate Professor of Immunobiology

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👥Biography 个人简介

Andrew Bhatt studies the epigenetic mechanisms that maintain FOXP3 expression and regulatory T cell lineage stability. His research has characterized the Treg-specific demethylated region upstream of FOXP3 and how its methylation status governs Treg stability under inflammatory conditions. He has investigated how tumor microenvironmental signals can destabilize FOXP3 expression and convert Tregs into pro-inflammatory cells. His work on Treg plasticity and stability has important implications for Treg-targeted cancer therapies.

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🧪Research Fields 研究领域

FOXP3 epigenetic regulation
Treg stability
Treg lineage
TSDR methylation
Treg plasticity

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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