Andrew Bhatt

Dr. Andrew Bhatt is a medicinal chemist and structural biologist at the University of Michigan who specializes in covalent drug design for cancer targets. His research focuses on the structure-based optimization of electrophilic warheads targeting cysteine residues in oncogenic proteins, most notably contributing to the mechanistic understanding of KRAS G12C-selective covalent inhibitors. He studies structure-activity relationships for improved potency and selectivity of irreversible oncology drugs.