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Translational Medicine / 转化医学ARV-110, AR Degraders, mCRPC

Andrew Armstrong

MD, MSc

🏢Duke Cancer Institute🌐USA

Professor of Medicine

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Key Contributions

👥Biography 个人简介

Andrew Armstrong at Duke Cancer Institute leads clinical development of novel androgen receptor-targeting approaches in mCRPC, including PROTAC AR degraders such as ARV-110. His research addresses mechanisms of enzalutamide and abiraterone resistance and how novel AR-targeting approaches can overcome them. He contributes to cooperative group trials and has published extensively on prognostic and predictive biomarkers in metastatic prostate cancer. His lab-to-clinic translational approach has advanced next-generation hormonal therapies.

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🧪Research Fields 研究领域

ARV-110 AR degrader
PROTAC prostate cancer
enzalutamide resistance mCRPC
androgen receptor degradation
mCRPC biomarkers

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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