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Translational Medicine / 转化医学Prime Editing, Precision Genome Editing

Andrew Anzalone

MD, PhD

🏢Columbia University🌐USA

Assistant Professor of Chemical Biology

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Key Contributions

👥Biography 个人简介

Andrew Anzalone developed prime editing technology as a graduate student in David Liu's laboratory, creating a versatile genome editing system capable of making all 12 types of point mutations, small insertions, and small deletions without double-strand DNA breaks. Prime editing has major implications for correcting the diverse mutations underlying hereditary cancer syndromes and acquired oncogenic mutations. He joined Columbia University where his laboratory continues to develop and apply next-generation genome editing tools. His work has been recognized with multiple prestigious early-career awards.

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🧪Research Fields 研究领域

prime editing
CRISPR
cancer gene correction
precision medicine
therapeutic genome editing

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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