Andrea Sottoriva
PhD
Professor of Computational Cancer Genomics
👥Biography 个人简介
Andrea Sottoriva proposed the Big Bang model of colorectal tumor growth, demonstrating that intratumor heterogeneity is established early and maintained through neutral evolution without stringent clonal selection. His mathematical frameworks for inferring evolutionary dynamics from genomic data have transformed understanding of how tumors evolve and diversify. He has established quantitative methods linking tumor evolution patterns to clinical outcomes.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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