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Translational Medicine / 转化医学Dostarlimab dMMR Rectal, Neoadjuvant IO

Andrea Cercek

MD

🏢Memorial Sloan Kettering Cancer Center🌐USA

Section Head, Colorectal Cancer

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Key Contributions

👥Biography 个人简介

Andrea Cercek led the landmark trial showing 100% complete clinical response to dostarlimab in dMMR rectal cancer, transforming the neoadjuvant management of MSI-H rectal cancer. Her work established immunotherapy as curative in locally advanced dMMR rectal disease.

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🧪Research Fields 研究领域

dostarlimab neoadjuvant
dMMR rectal cancer
organ preservation
complete clinical response
NICHE-2

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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