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Translational Medicine / 转化医学Hippo/YAP Pathway, Liver Cancer

Andrea Bhatt

MD

🏢Vanderbilt University Medical Center🌐USA

Associate Professor of Gastroenterology

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👥Biography 个人简介

Andrea Bhatt specializes in Hippo pathway biology in the liver, investigating its roles in liver regeneration and hepatocellular carcinoma development. Her research has demonstrated how loss of Hippo signaling drives hepatic overgrowth and tumor formation in mouse models. She has characterized YAP-driven transcriptional programs in HCC and their dependence on co-activators TEAD1-4. Her work has identified Hippo pathway components as prognostic biomarkers and therapeutic targets in liver cancer.

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🧪Research Fields 研究领域

hepatocellular carcinoma Hippo
YAP in liver regeneration
cholangiocarcinoma
liver tumor microenvironment
Hippo liver biology

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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