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Translational Medicine / 转化医学Hodgkin Lymphoma, Brentuximab Vedotin

Anas Younes

MD

🏢Memorial Sloan Kettering Cancer Center🌐USA

Chief, Lymphoma Service

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Key Contributions

👥Biography 个人简介

Anas Younes at MSK has contributed to lymphoma research including development of brentuximab vedotin (anti-CD30 ADC) for relapsed Hodgkin lymphoma and anaplastic large cell lymphoma, and to trials incorporating brentuximab into frontline Hodgkin therapy (ECHELON-1). He has also contributed to PD-1 checkpoint inhibitor development in Hodgkin lymphoma — a particularly sensitive cancer due to 9p24.1 amplification that increases PD-L1 expression.

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🧪Research Fields 研究领域

brentuximab vedotin Hodgkin lymphoma
ECHELON-1 ABVD brentuximab
anti-CD30 ADC Hodgkin lymphoma
PD-1 nivolumab Hodgkin lymphoma
classic Hodgkin lymphoma treatment

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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