Ana Oaknin
安娜·奥克宁
MD, PhD
Head, Gynecological Tumors Unit; Senior Investigator妇科肿瘤组主任；高级研究员
👥Biography 个人简介
Ana Oaknin, MD, PhD leads the Gynecological Tumors Unit at VHIO in Barcelona. A major contributor to SOLO-1 and SOLO-2 olaparib trials, she also investigates antibody-drug conjugates including mirvetuximab soravtansine for FRα-positive ovarian cancer. She is a leading European voice on novel gynecologic oncology therapeutics.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
SOLO-1 and SOLO-2 Olaparib Maintenance Trials
Key investigator in the SOLO-1 (first-line) and SOLO-2 (recurrent) olaparib maintenance trials, which established olaparib as standard maintenance therapy in BRCA-mutated advanced ovarian cancer.
Mirvetuximab Soravtansine and FRα-Targeted Therapy
Investigated mirvetuximab soravtansine in FRα-positive platinum-resistant ovarian cancer, contributing to its approval as the first antibody-drug conjugate for ovarian cancer in Europe.
Representative Works 代表性著作
Olaparib tablets as maintenance therapy in patients with platinum-sensitive, relapsed ovarian cancer (SOLO-2/ENGOT-Ov21)
The Lancet Oncology (2017)
Phase III trial showing olaparib tablets significantly prolonged progression-free survival in BRCA-mutated, platinum-sensitive recurrent ovarian cancer.
Mirvetuximab Soravtansine in FRα-Positive, Platinum-Resistant Ovarian Cancer
New England Journal of Medicine (2023)
Demonstrated superior response rate and survival benefit of mirvetuximab soravtansine over investigator's choice chemotherapy in this challenging population.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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关注 安娜·奥克宁 的研究动态
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留下邮箱，当我们发布与 Ana Oaknin（Vall d'Hebron University Hospital / Vall d'Hebron Institute of Oncology (VHIO)）相关的新研究或访谈时，我们会通知你。
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