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Translational Medicine / 转化医学Endometrial Carcinosarcoma Pembrolizumab, RUBY Trial

Ana Oaknin

MD, PhD

🏢Vall d'Hebron University Hospital / Vall d'Hebron Institute of Oncology🌐Spain

Head, Gynecologic Cancer Program

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Key Contributions

👥Biography 个人简介

Ana Oaknin is a gynecologic oncologist at Vall d'Hebron and ENGOT collaborator who has been a principal investigator on the RUBY trial of dostarlimab plus carboplatin-paclitaxel for endometrial cancer including carcinosarcoma histology. Her work has demonstrated that carcinosarcoma patients included in immunotherapy trials of endometrial cancer can achieve responses when tumors are dMMR or POLE-mutated, and she has contributed to subgroup analyses informing the approval of pembrolizumab and dostarlimab in carcinosarcoma. She co-chairs GEICO Spanish gynecologic oncology group.

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🧪Research Fields 研究领域

pembrolizumab carcinosarcoma endometrial RUBY
RUBY dostarlimab carcinosarcoma
endometrial cancer immune checkpoint
ENGOT carcinosarcoma clinical trials Spain
gynecologic malignancy immunotherapy IO

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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