Amrita Krishnan
阿姆里塔·克里希南
MD
Director, Judy and Bernard Briskin Center for Multiple Myeloma Research多发性骨髓瘤研究中心主任
👥Biography 个人简介
Amrita Krishnan directs the myeloma program at City of Hope and is a national leader in stem cell transplantation and cellular therapy for myeloma. She has pioneered allogeneic SCT approaches and contributed to advancing CAR-T manufacturing platforms at a high-volume transplant center.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Allogeneic SCT in Myeloma
Investigated the role of allogeneic stem cell transplantation including reduced-intensity conditioning regimens in relapsed/refractory myeloma, defining patient populations likely to benefit from graft-versus-myeloma effects.
CAR-T Manufacturing and Logistics
Led City of Hope initiatives optimizing the manufacturing pipeline, vein-to-vein time, and bridging therapy strategies for BCMA-directed CAR-T therapies in heavily pretreated myeloma patients.
Novel Conditioning Regimens for Myeloma Transplant
Developed and tested novel conditioning regimens incorporating targeted radionuclide therapy and novel agents to reduce disease burden prior to autologous and allogeneic transplantation in high-risk myeloma.
Representative Works 代表性著作
Allogeneic Transplantation for Multiple Myeloma: Outcomes and Predictors
Biology of Blood and Marrow Transplantation (2020)
Analysis of long-term outcomes after allogeneic SCT for myeloma, identifying prognostic factors for disease control and survival.
CAR-T Cell Therapy in Myeloma: Practical Considerations for High-Volume Centers
Transplantation and Cellular Therapy (2022)
Operational framework for implementing commercial BCMA CAR-T programs at large academic transplant centers.
Optimizing Bridging Therapy Prior to BCMA CAR-T in Relapsed Myeloma
Blood Advances (2023)
Retrospective analysis examining impact of bridging therapy choice on CAR-T expansion and clinical outcomes in myeloma patients.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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