Amit G. Singal
阿米特·辛格尔
MD, MS
Professor of Medicine; Chief of Hepatology内科学教授；肝病科主任
👥Biography 个人简介
Amit Singal is the leading authority on HCC surveillance and early detection, particularly in cirrhotic populations. His GALAD score research and PIVKA-II/AFP biomarker studies have transformed screening guidelines, and he leads real-world HCC outcomes programs at UT Southwestern.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
HCC Surveillance and Biomarkers
Developed and validated the GALAD score combining AFP, AFP-L3, and PIVKA-II for early HCC detection, showing superior sensitivity over ultrasound-only surveillance in cirrhosis.
Real-World HCC Outcomes
Led population-level studies demonstrating gaps in HCC surveillance adherence and their impact on stage at diagnosis and survival, informing public health interventions.
Representative Works 代表性著作
GALAD Score Identifies Patients with HCC Detected by Biomarker Testing vs. Ultrasound
Clinical Gastroenterology and Hepatology (2022)
Prospective validation of GALAD score for early HCC detection in U.S. cirrhosis cohorts, supporting inclusion in surveillance algorithms.
HCC Surveillance in Patients with Cirrhosis: Practice Patterns and Outcomes
Hepatology (2019)
Nationwide analysis demonstrating real-world surveillance gaps and their correlation with advanced-stage diagnosis and reduced survival.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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