Aminah Jatoi
阿米纳·贾托伊
MD
Professor of Oncology, Department of Oncology肿瘤科肿瘤学教授
👥Biography 个人简介
Aminah Jatoi is a leading clinical trialist at Mayo Clinic specializing in cancer anorexia-cachexia syndrome. She has conducted pivotal randomized trials of pharmacological interventions including megestrol acetate, cannabinoids, and anti-inflammatory agents, shaping evidence-based supportive care guidelines.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Pharmacological Appetite Stimulation
Conducted landmark comparative clinical trials of appetite stimulants including megestrol acetate, dronabinol, and combination regimens, clarifying their efficacy and safety profiles in cancer anorexia.
Anti-cytokine Strategies in Cachexia
Investigated TNF-alpha inhibitors and other anti-inflammatory agents as treatments for cancer cachexia, advancing understanding of cytokine-mediated wasting mechanisms.
Patient-Reported Outcome Research
Integrated patient-reported outcomes including appetite, quality of life, and functional status into cachexia clinical trials, establishing patient-centered endpoints as primary measures.
Representative Works 代表性著作
Dronabinol versus megestrol acetate versus combination therapy for cancer-associated anorexia
Journal of Clinical Oncology (2002)
Pivotal three-arm randomized trial establishing megestrol acetate as superior to dronabinol for cancer-related anorexia, directly influencing clinical practice guidelines.
A placebo-controlled, double-blind trial of infliximab for cancer-associated weight loss
American Journal of Clinical Oncology (2010)
Randomized trial evaluating TNF inhibition in cancer cachexia, providing key data on anti-cytokine approach limitations in this setting.
Cancer anorexia-cachexia syndrome: further exploration of endocannabinoids and contextual factors
Oncologist (2013)
Review synthesizing clinical trial evidence for cannabinoid-based interventions in cancer anorexia, guiding future research directions.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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