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Translational Medicine / 转化医学Milestone IO Approvals

James Allison

PhD

🏢MD Anderson Cancer Center🌐USA

Chair, Department of Immunology; Executive Director, Immunotherapy Platform

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Key Contributions

👥Biography 个人简介

James Allison discovered that CTLA-4 blockade could unleash antitumor T cell responses, leading to FDA approval of ipilimumab for melanoma in 2011 and opening the modern era of cancer immunotherapy. He shared the 2018 Nobel Prize in Physiology or Medicine with Tasuku Honjo. He chairs immunology at MD Anderson.

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🧪Research Fields 研究领域

CTLA-4
ipilimumab
Nobel Prize 2018
checkpoint blockade
immunotherapy pioneer

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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