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Translational Medicine / 转化医学Milestone 800 Oncology Figures

James Allison

PhD

🏢MD Anderson Cancer Center🌐USA

Chair, Department of Immunology

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Key Contributions

👥Biography 个人简介

James Allison received the 2018 Nobel Prize in Physiology or Medicine for his discovery of cancer therapy by inhibition of negative immune regulation through CTLA-4 blockade. His development of ipilimumab as the first checkpoint immunotherapy revolutionized cancer treatment across multiple tumor types. His work launched the modern era of cancer immunotherapy.

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🧪Research Fields 研究领域

CTLA-4 checkpoint
Ipilimumab
Cancer immunotherapy
T cell biology
Nobel Prize Medicine 2018

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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