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Translational Medicine / 转化医学Bone Metastasis, Denosumab

Alison Stopeck

MD

🏢Stony Brook Cancer Center🌐USA

Professor of Medicine; Chief, Division of Hematology and Oncology

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👥Biography 个人简介

Alison Stopeck led the landmark phase 3 trial demonstrating non-inferiority of denosumab versus zoledronic acid for prevention of skeletal-related events in breast cancer bone metastases. Her research has contributed to defining optimal bone-targeted therapy selection and monitoring in metastatic breast cancer. She investigates biomarkers of bone turnover and predictors of skeletal events. She has shaped national guidelines for bone health management in oncology and is an active educator in the field of supportive oncology.

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🧪Research Fields 研究领域

denosumab bone metastases
RANK ligand inhibition
breast cancer bone metastases
skeletal-related events
denosumab versus zoledronate comparison

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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